Potassium iodide and the wolff-chaikoff effect: relevance for the dermatologist.

Heymann, W R · J Am Acad Dermatol · 2000

review · Level V

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Abstract

The inhibition of organic binding of iodide in the thyroid gland by excess iodide, resulting in the cessation of thyroid hormone synthesis, is known as the Wolff-Chaikoff effect. This review explores the nature of the Wolff-Chaikoff effect, both in terms of its potential mechanisms and its relevance to dermatologists who use potassium iodide as a therapeutic agent.

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