Vasculitic neuropathy in a patient with inactive treated lepromatous leprosy.
case_report · Level V
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- Record sourced from PubMed, PMID 10727487.
- Also identified by PMC identifier 1736894.
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Abstract
A 46 year old Asian male with previously treated lepromatous leprosy developed a stepwise multifocal sensory disturbance 25 years later. Neurophysiology demonstrated marked deterioration from previous studies. Sural nerve biopsy disclosed a vasculitic process superimposed on inactive lepromatous leprosy. Immunocytochemical stains for mycobacterial antigen showed deposits within nerve and vessel walls. A delayed vasculitic neuropathy precipitated by persisting mycobacterial antigen is proposed.
Medical subject headings
- Leprosy, Lepromatous
- Peripheral Nervous System Diseases
- Vasculitis