A new cause of 'non-responsiveness' in coeliac disease?
case_report · Level V
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- Record sourced from PubMed, PMID 10727567.
- Also identified by PMC identifier 1741565.
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Abstract
A 42 year old man presented with gluten-responsive coeliac disease and secondary pancreatic insufficiency. Subsequently his symptoms relapsed and repeat small intestinal biopsy showed villous atrophy and infiltration by leukaemic cells, despite continuation of a gluten-free diet. Serious causes of relapse and non-responsiveness in coeliac disease include enteropathy-associated T-cell lymphoma, ulcerative jejunitis and an end-stage hypoplastic mucosa. This is the first report of non-responsiveness due to infiltration by leukaemia.
Medical subject headings
- Celiac Disease
- Intestine, Small
- Leukemia, Myelomonocytic, Chronic
- Leukemic Infiltration