Mechanisms of angiogenesis and arteriogenesis.
review · Level V
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Abstract
Endothelial and smooth muscle cells interact with each other to form new blood vessels. In this review, the cellular and molecular mechanisms underlying the formation of endothelium-lined channels (angiogenesis) and their maturation via recruitment of smooth muscle cells (arteriogenesis) during physiological and pathological conditions are summarized, alongside with possible therapeutic applications.
Medical subject headings
- Arterioles
- Neovascularization, Pathologic