Physostigmine in the treatment of gamma-hydroxybutyric acid overdose.
case_report · Level V
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- Record sourced from PubMed, PMID 10761496.
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Abstract
The widespread abuse of the recreational drug gamma-hydroxybutyric acid has resulted in several reports of overdose leading to coma. The use of a short-acting anticholinesterase agent such as physostigmine as a potential reversal agent has been proposed previously. We report 2 cases of gamma-hydroxybutyric acid-induced coma that rapidly reversed with intravenous administration of physostigmine.
Medical subject headings
- Cholinesterase Inhibitors
- Hydroxybutyrates
- Physostigmine