A case of bilateral optic neuropathy in a patient on tacrolimus (FK506) therapy after liver transplantation.
case_report · Level V
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- Record sourced from PubMed, PMID 10764869.
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Abstract
To report a case of bilateral optic neuropathy in a patient receiving tacrolimus (FK 506, Prograf; Fujisawa USA, Inc, Deerfield, Illinois) for immunosuppression after orthotropic liver transplantation. Case report. In a 58-year-old man receiving tacrolimus after orthotropic liver transplantation, serial neuro-ophthalmologic examinations and laboratory studies were performed. The patient had episodic deterioration of vision in both eyes, with clinical features resembling ischemic optic neuropathies. Deterioration of vision occurred despite discontinuation of the tacrolimus. Tacrolimus and other immunosuppressive agents may be associated with optic nerve toxicity.
Medical subject headings
- Graft Rejection
- Immunosuppressive Agents
- Liver Transplantation
- Optic Nerve Diseases
- Tacrolimus