A retrospective study of surgical and conservative treatment for spinal extradural abscess.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 10766080.
- Also identified by PMC identifier 3611342.
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Abstract
The management of spinal extradural abscess (SEA), particularly the choice between surgical and conservative treatment, is controversial. We therefore undertook a retrospective study of patients admitted with this diagnosis: Details of presentation, treatment and outcome were obtained by review of inpatient notes and radiology. Twenty-five individuals with SEA aged 10-79 years were admitted between 1989 and 1995. Nine were treated non-operatively with antibiotics, of which three also underwent diagnostic CT-guided biopsy, and 16 underwent surgical drainage. There was no significant difference in the neurological features at presentation between the two groups. Two patients (8%) died; 11 (44%) patients remained the same and 12 (48%) improved following treatment. Four patients treated conservatively (44%) and seven treated surgically (43%) were capable of return to work or school, whilst a further seven patients (three treated conservatively and four treated surgically) were able to lead independent lives. No significant difference in outcome was demonstrated between patients treated non-operatively and those treated surgically. We conclude that certain carefully selected patients can be treated conservatively, but that surgery should remain the mainstay of management.
Medical subject headings
- Abscess
- Anti-Bacterial Agents
- Drug Therapy, Combination
- Spinal Diseases
- Suction