Scleromyxedema with dermato-neuro syndrome.

Gonzalez, J; Palangio, M; Schwartz, J; Klainer, A S; Bisaccia, E · J Am Acad Dermatol · 2000

case_report · Level V

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Abstract

Scleromyxedema is a rare connective tissue disease of unknown cause characterized by a generalized papular eruption, dermal fibroblast proliferation, and monoclonal paraproteinemia. A paroxysmal triad consisting of high fever, seizures, and coma with a flu-like prodrome can rarely occur in patients with scleromyxedema and is termed "dermato-neuro syndrome." We describe a 41-year-old patient with scleromyxedema in whom the dermato-neuro syndrome developed.

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