Antibiotic beads in the treatment of diabetic pedal osteomyelitis.

Roeder, B; Van Gils, C C; Maling, S · J Foot Ankle Surg · 2000

review · Level V

Where this comes from

Abstract

Antibiotic-impregnated polymethylmethacrylate (PMMA) beads have improved the outcome of osteomyelitis treatment in both experimental models and clinical trials. The primary benefit of antibiotic-impregnated PMMA beads is that they provide high local concentrations of antibiotic while systemic levels of antibiotic remain low. Little has been written about the specific use of antibiotic-impregnated PMMA beads in the treatment of diabetic pedal osteomyelitis. The authors review antibiotic-impregnated PMMA beads and provide examples of their use in the treatment of diabetic pedal osteomyelitis.

Medical subject headings

Anatomy