Rectally administered dimenhydrinate reduces postoperative vomiting in children after strabismus surgery.
rct · Level II
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Abstract
We have investigated the effectiveness of rectally administered dimenhydrinate on postoperative vomiting in children undergoing strabismus surgery, in a double-blind, randomized, placebo-controlled study. In one group, dimenhydrinate 50 mg was administered rectally 30 min before starting anaesthesia, whereas in the control group, placebo suppositories were given. Children who received dimenhydrinate showed a significantly (P < 0.001) lower incidence of vomiting (15%) than those in the control group (75%). We conclude that rectal administration of dimenhydrinate is an effective means of reducing postoperative vomiting in children undergoing strabismus surgery.
Medical subject headings
- Antiemetics
- Dimenhydrinate
- Postoperative Nausea and Vomiting
- Strabismus