Radiobiological depth of subcutaneous induration.

Nuutinen, J; Väänänen, A; Lahtinen, T; Turunen, M; Remes, S; Alanen, E · Radiother Oncol · 2000

case_series · Level IV

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Abstract

The incidence of subcutaneous induration in 23 breast cancer patients with postmastectomy radiotherapy was investigated. The patients were treated with three different radiotherapy schedules 7. 9-9.8 years ago. The incidence was correlated with the biological effective dose (BED) at different depths from the skin surface and a best fit was obtained using an alpha/beta ratio of 2 Gy. The most representative depth at which to assess dose for subcutaneous induration was 2 mm which is near the subcutaneous fat/dermis interface.

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