Odorant inhalation affects skin barrier homeostasis in mice and humans.
prospective_cohort · Level II
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Abstract
Previous studies have suggested that psychological stress delays cutaneous barrier recovery following acute barrier disruption, and that sedative drugs block this delay. A sedative effect of some odorants has been reported. In the present study, we demonstrate that odorant inhalation affects cutaneous barrier homeostasis in both mice and humans. Odorants with a sedative effect prevented the delay of skin barrier recovery induced by stress after acute barrier disruption. Other odorants did not show this effect.
Medical subject headings
- Benzene Derivatives
- Homeostasis
- Hypnotics and Sedatives
- Oils, Volatile
- Skin Physiological Phenomena