Identification of monozygotic twins that are concordant for preeclampsia.

O'shaughnessy, K M; Ferraro, F; Fu, B; Downing, S; Morris, N H · Am J Obstet Gynecol · 2000

case_series · Level IV

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Abstract

Preeclampsia is thought to be discordant in monozygotic twins. While recruiting for a genetic study into preeclampsia, we identified 4 sets of twins and a triplet gestation; all were monozygous on deoxyribonucleic acid "fingerprinting." Two twins were concordant for preeclampsia, and 2 of the triplets had pregnancy-induced hypertension, although only 1 of them had proteinuria. Hence we confirm the existence of monozygotic twins that are concordant for preeclampsia.

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