Human leukocyte antigen-G: immunotolerant major histocompatibility complex molecule in transplantation.
review · Level V
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Abstract
HLA-G is a nonclassical major histocompatibility complex class I molecule selectively expressed on cytotrophoblasts at the fetal-maternal interface, where it plays a role in maternofetal tolerance. In this review, attempts were made to summarize the current state of knowledge of the effects of HLA-G on both natural killer cell and T cell functions and their implications in transplantation.
Medical subject headings
- HLA Antigens
- Histocompatibility Antigens Class I
- Killer Cells, Natural
- Major Histocompatibility Complex
- T-Lymphocytes
- Transplantation Immunology