Primary cutaneous B cell lymphoma during methotrexate therapy for rheumatoid arthritis.
case_report · Level V
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- Record sourced from PubMed, PMID 10852288.
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Abstract
A patient with rheumatoid arthritis developed a reversible, primary cutaneous, large B cell lymphoma during prolonged methotrexate (MTX) treatment. Regression of the skin lesions after discontinuation of the drug suggested a close relationship to MTX. Increased clinical awareness, discontinuation of MTX, and close observation are important in the initial management of this rare lymphoproliferative disorder.
Medical subject headings
- Antirheumatic Agents
- Arthritis, Rheumatoid
- Lymphoma, B-Cell
- Methotrexate
- Skin Neoplasms