Mechanisms to explain pancreatic dysfunction in cystic fibrosis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 10872422.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
This article focuses on three potential mechanisms by which pancreatic dysfunction occurs in cystic fibrosis. These include (1) obstruction of pancreatic ducts by inspissated plugs, (2) inhibition of endocytosis in acinar cells, and (3) imbalance in membrane lipids in cystic fibrosis regulated cells. Any of these abnormalities alone or in combination may explain the development of pancreatic exocrine insufficiency.
Medical subject headings
- Cystic Fibrosis
- Exocrine Pancreatic Insufficiency
- Pancreas