Recurrent blastomycosis of the central nervous system: case report and review.

Chowfin, A; Tight, R; Mitchell, S · Clin Infect Dis · 2000

case_report · Level V

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Abstract

Although blastomycosis of the central nervous system (CNS) occurs in approximately 4% of patients with blastomycosis, recurrent CNS blastomycosis is very rare. We review the clinical features, treatment, and outcome of 4 previously reported cases. We also report a case of recurrent CNS blastomycosis successfully treated with surgery and liposomal amphotericin B after an inadequate response to amphotericin B therapy. This treatment may be an alternate approach for management of similar cases.

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