The use of growth factors in cartilage repair.

O'Connor, W J; Botti, T; Khan, S N; Lane, J M · Orthop Clin North Am · 2000

review · Level V

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Abstract

Articular cartilage, which enables smooth gliding of joints during skeletal motion, is vulnerable to injuries and degenerative diseases over time. Bone growth factors have a role in the preservation of the cartilage matrix. This article reviews the potential to treat cartilage damage for bone morphogenetic proteins, insulin-like growth factors, hepatocyte growth factor, basic fibroblast growth factor, and transforming growth factor beta.

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