Large plantar wart caused by human papillomavirus-66 and resolution by topical cidofovir therapy.

Davis, M D; Gostout, B S; McGovern, R M; Persing, D H; Schut, R L; Pittelkow, M R · J Am Acad Dermatol · 2000

case_report · Level V

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Abstract

Warts can be difficult to diagnose and to treat in the setting of human immunodeficiency virus (HIV) infection. A 37-year-old woman with a background of HIV presented with a large verrucous plaque involving her right foot. Human papillomavirus (HPV)-66 was identified in the lesional skin biopsy sample and in scrapings obtained from her cervix. The wart rapidly responded to topical cidofovir therapy. HPV-66 is a novel HPV type to be associated with verruca vulgaris. Topical cidofovir should be further investigated as an alternative treatment modality for verruca vulgaris.

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