An unusual concurrence of graft versus host disease caused by engraftment of maternal lymphocytes with DiGeorge anomaly.

Ocejo-Vinyals, J G; Lozano, M J; Sánchez-Velasco, P; Escribano de Diego, J; Paz-Miguel, J E; Leyva-Cobián, F · Arch Dis Child · 2000

case_report · Level V

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Abstract

We describe a girl with DiGeorge anomaly and normal cytogenetic and molecular studies, whose clinical course was complicated by graft versus host disease caused by intrauterine materno-fetal transfusion, and several immunohematological alterations including a monoclonal gammapathy of undetermined significance (first IgG, which subsequently changed to IgM). The main clinical features and pathological findings are discussed.

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