Unexpected corneal endothelial cell decompensation after intraocular surgery with instruments sterilized by plasma gas.

Abstract

Ten cases of unexpected corneal endothelial cell decompensation occurring after routine intraocular surgery using instruments sterilized with a new plasma gas protocol are described. A retrospective observational case series with 1 year of follow-up was conducted. All patients had corneal decompensation and nonreactive pupils after surgery. Six patients required penetrating keratoplasty. Three patients partially recovered pupillary function. Visual acuity at 1 year ranged from 20/20 to hand motion (HM). One patient with an anterior chamber intraocular lens (ACIOL) experienced optic atrophy and HM vision despite resolution of corneal edema. Toxic corneal endothelial cell destruction syndrome was associated with the introduction of plasma gas sterilization protocols.