Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 10932210.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Cells from the telomerase knockout mouse immortalize with an approximately ten million-fold greater frequency than human cells. In this commentary, Wright and Shay discuss the implications of this difference between mice and men and its relationship to cancer.
Medical subject headings
- Neoplasms
- Telomere