Recalcitrant pyoderma gangrenosum treated with thalidomide.
case_report · Level V
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- Record sourced from PubMed, PMID 10943240.
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Abstract
Pyoderma gangrenosum is a painful, noninfectious, ulcerating skin disorder often associated with systemic disease. Thalidomide has been used to treat many inflammatory dermatologic conditions and has been reintroduced in the United States to treat immune-modulated diseases such as pyoderma gangrenosum. The patient described, a 47-year-old man, had histologically confirmed pyoderma gangrenosum that did not respond to treatment with several courses of methylprednisolone. The ulcer healed with 10 weeks of oral thalidomide administration.
Medical subject headings
- Dermatologic Agents
- Pyoderma Gangrenosum
- Thalidomide