Testosterone replacement and the physiologic aspects of aging in men.

Morley, J E · Mayo Clin Proc · 2000

review · Level V

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Abstract

Clinical and epidemiologic studies, along with basic scientific research, have shown a trend toward androgen deficiency in aging males. The focus of the clinical investigations described here is to determine whether testosterone deficiency is a physiologic cause of the aging process and whether testosterone replacement might prevent or ameliorate a decline in quality of life associated with age-related decline in physical and psychological functioning.

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