Acute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide.

Felmet, K; Robins, B; Tilford, D; Hayflick, S J · J Pediatr · 2000

case_report · Level V

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Abstract

After exposure to nitrous oxide, an infant with unrecognized cobalamin deficiency developed neurologic deterioration and pancytopenia. Hematologic recovery and partial resolution of his neurologic changes followed repletion of the vitamin. Nitrous oxide depletes bioavailable cobalamin and may be a dangerous anesthetic in patients with cobalamin deficiency.

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