No tissue damage by chronic deep brain stimulation in Parkinson's disease.
case_series · Level IV
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- Record sourced from PubMed, PMID 10976644.
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Abstract
We report on the pathological findings in the brains of 8 Parkinson's disease patients treated with deep brain stimulation (DBS) of the thalamic ventral intermediate nucleus (6 cases) and subthalamic nucleus (2 cases). DBS was performed continuously for up to 70 months. All brains showed well-preserved neural parenchyma and only mild gliosis around the lead track compatible with reactive changes due to surgical placement of the electrode. We conclude that chronic DBS does not cause damage to adjacent brain tissue.
Medical subject headings
- Brain
- Electric Stimulation Therapy
- Parkinson Disease