Repeated quantitative perfusion and contrast permeability measurement in the MRI examination of a CNS tumor.

Abstract

This study reports on the results of quantitative MRI perfusion and contrast permeability measurement on two occasions in one patient. The measurements were separated 81 days in time. The tumor grew considerably in this period, but no change was found with respect to perfusion and contrast permeability. Non-involved white matter values were reproduced to demonstrate repeatability. The presented approach to dynamic susceptibility contrast MRI allows fast and repeatable quantitative assessment of perfusion and is easily integrated in a conventional brain tumor protocol.