Neuroblastomatous recurrence of ganglioglioma. Case report.

David, K M; de Sanctis, S; Lewis, P D; Noury, A M; Edwards, J M · J Neurosurg · 2000

case_report · Level V

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Abstract

This case is believed to be the first reported recurrent intracranial ganglioglioma with purely neuroblastomatous malignant transformation. A complete macroscopic resection of a right frontal lobe tumor in an 18-year-old woman revealed differentiated ganglioglioma. Seven years later a large, well-demarcated recurrent tumor was again macroscopically totally resected in the same patient. Histological analysis showed malignant transformation in only the neuronal component of the original tumor. A review of the literature on recurrent gangliogliomas and their malignant transformation is included.

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