Vancomycin-induced neutropenia resolves after substitution with teicoplanin.

Sanche, S E; Dust, W N; Shevchuk, Y M · Clin Infect Dis · 2000

case_report · Level V

Where this comes from

Abstract

Neutropenia is an uncommon adverse effect associated with prolonged vancomycin therapy. Neutrophil counts normally recover after discontinuation of vancomycin in this situation, but treatment options are needed for those patients who require ongoing antibiotic therapy. We describe a case of vancomycin-induced neutropenia in which the neutropenia resolved after vancomycin was replaced by the structurally related compound teicoplanin.

Medical subject headings