Decoding calcium signals involved in cardiac growth and function.
review · Level V
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- Record sourced from PubMed, PMID 11062532.
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Abstract
Calcium is central in the regulation of cardiac contractility, growth and gene expression. Variations in the amplitude, frequency and compartmentalization of calcium signals are decoded by calcium/calmodulin-dependent enzymes, ion channels and transcription factors. Understanding the circuitry for calcium signaling creates opportunities for pharmacological modification of cardiac function.
Medical subject headings
- Calcium Signaling
- Heart
- Myocardial Contraction