Pancreatic tumors show high levels of hypoxia.
case_series · Level IV
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- Record sourced from PubMed, PMID 11072146.
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Abstract
Because of the dismal outcomes of conventional therapies for pancreatic carcinomas, we postulated that hypoxia may exist within these tumors. Seven sequential patients with adenocarcinomas of the pancreas consented to intraoperative measurements of tumor oxygenation using the Eppendorf (Hamburg, Germany) polargraphic electrode. All 7 tumors demonstrated significant tumor hypoxia. In contrast, adjacent normal pancreas showed normal oxygenation. Tumor hypoxia exists within pancreatic cancers.
Medical subject headings
- Cell Hypoxia
- Oxygen
- Pancreas
- Pancreatic Neoplasms