Discontinuation of anticonvulsant therapy in children with partial epilepsy.

Verrotti, A; Morresi, S; Basciani, F; Cutarella, R; Morgese, G; Chiarelli, F · Neurology · 2000

prospective_cohort · Level II

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Abstract

To evaluate when it is possible to discontinue anticonvulsant treatment in children with cryptogenic partial epilepsy, the authors studied 89 epileptic children divided into two groups: Group A, 45 children whose therapy was discontinued after 1 year from the last seizure; and Group B, 44 children whose therapy was stopped after 2 years from the last seizure. After 5 years of follow-up, the recurrence rate was similar in the two groups of patients (Group A, 28.8%; Group B, 25%). It is safe to discontinue the anticonvulsant therapy in children with cryptogenic partial epilepsy who were seizure free for only 1 year.

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