Increase of macrophage migration inhibitory factor in sera of patients with iridocyclitis.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 11090487.
- Also identified by PMC identifier 1723331.
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Abstract
To determine whether macrophage migration inhibitory factor (MIF) levels were increased in sera of the patients with iridocyclitis. Sera were obtained from 41 patients with acute iridocyclitis, 13 patients with chronic iridocyclitis, and 44 healthy control subjects. MIF levels were determined by a human MIF ELISA. The average levels of MIF in the sera of patients with both acute and chronic iridocyclitis were significantly higher than that of healthy subjects. Uveitis induces the elevation of serum MIF, which may affect various inflammatory symptoms in uveitis.
Medical subject headings
- Iridocyclitis
- Macrophage Migration-Inhibitory Factors