Acute renal failure: unusual complication of Epstein-Barr virus-induced infectious mononucleosis.
case_report · Level V
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Abstract
A 17-year-old boy with juvenile rheumatoid arthritis presented with jaundice, confusion, hemolytic anemia, thrombocytopenia, and acute renal failure secondary to titer-confirmed acute Epstein-Barr virus (EBV). Renal biopsy specimen revealed interstitial nephritis with an inflammatory infiltrate composed of cytotoxic/suppressor T cells, and interstitial mononuclear cell nuclei expressed EBV encoded RNA-1 (EBER-1) mRNA. Methylprednisolone treatment resulted in rapid improvement.
Medical subject headings
- Acute Kidney Injury
- Herpesvirus 4, Human
- Infectious Mononucleosis