The pathology of REM sleep behavior disorder with comorbid Lewy body dementia.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 11113232.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A patient with REM sleep behavior disorder who subsequently developed probable Lewy body dementia is now reported to have a definite pathologic diagnosis of Lewy body dementia. Examination of brain revealed Lewy bodies as well as marked neuronal loss in brainstem monoaminergic nuclei-particularly locus coeruleus and substantia nigra-that inhibit cholinergic neurons in the pedunculopontine nucleus mediating atonia during REM sleep.
Medical subject headings
- Brain
- Lewy Body Disease
- Sleep Wake Disorders