Use of topical cyclosporin for conjunctival manifestations of actinic prurigo.

Abstract

To report the successful treatment of conjunctival manifestations of actinic prurigo with topical cyclosporin. A 12-year-old female with extensive limbal lesions and chronic conjunctivitis secondary to actinic prurigo was treated with topical cyclosporin, and a rapid clinical response was observed. The patient had the limbal lesions surgically excised. The lesions completely recurred over the first 2 postoperative months. Treatment with topical steroids and vitamin A ointment was unsuccessful. The patient was then treated with cyclosporine 2% drops and a dramatic improvement occurred. Over a 3-month period, the lesions completely resolved. Cyclosporine eyedrops may be an effective treatment for the conjunctival manifestations of actinic prurigo.