Effect of subthalamic nucleus stimulation on levodopa-induced dyskinesia in Parkinson's disease.

Fraix, V; Pollak, P; Van Blercom, N; Xie, J; Krack, P; Koudsie, A; Benabid, A L · Neurology · 2000

case_series · Level IV

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Abstract

Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.

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