Yersinia lead SUMO attack.

Cornelis, G R; Denecker, G · Nat Med · 2001

basic_science · Level V

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Abstract

Little is known about the mechanism by which Yops, proteins that Yersinia inject into the cytosol of macrophage, cause downregulation of the inflammatory response and diseases such as the plague. Now it appears that Yops are the first bacterial member of a new family of ubiquitin-like proteases.

Medical subject headings