Progress in cardiovascular biology: PPAR for the course.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 11135607.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Studies on mice lacking the peroxisome proliferator-activated receptor (PPAR) suggest that PPAR ligands reduce lipid accumulation in foamy macrophages, and may target other receptors. These findings warrant an in-depth investigation into the gene regulatory mechanisms of PPAR ligands, which are currently being developed as drugs to treat atherosclerosis and diabetes.
Medical subject headings
- Cardiovascular Physiological Phenomena
- Receptors, Cytoplasmic and Nuclear
- Transcription Factors