NO vascular control in Duchenne muscular dystrophy.
basic_science · Level V
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- Record sourced from PubMed, PMID 11135610.
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Abstract
A new investigation into Duchenne muscular dystrophy (DMD) pathogenesis suggests that at least part of the muscle degeneration observed in DMD patients may result from the reduced production of muscle membrane-associated neuronal nitric oxide synthase. This reduction may lead to impaired regulation of the vasoconstrictor response and eventual muscle damage.
Medical subject headings
- Muscular Dystrophy, Duchenne
- Nitric Oxide
- Nitric Oxide Synthase
- Vasoconstriction