Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children.

Kline, R M; Kline, J J; Barbero, G J · J Pediatr · 2001

rct · Level II

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Abstract

In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.

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