Growth hormone deficiency caused by pituitary stalk interruption in Fanconi's anemia.
case_series · Level IV
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- Record sourced from PubMed, PMID 11148528.
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Abstract
Fanconi's anemia can be associated with growth retardation. We describe biologic growth hormone deficiency, isolated or associated with thyrotropin abnormality, and pituitary stalk interruption syndrome on magnetic resonance imaging of 5 patients with Fanconi's anemia. Growth hormone treatment produced catch-up growth in all cases. These findings suggest a common genetic origin.
Medical subject headings
- Fanconi Anemia
- Growth Disorders
- Human Growth Hormone
- Pituitary Gland