The use of lepirudin for anticoagulation in patients with heparin-induced thrombocytopenia during major vascular surgery.
case_report · Level V
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Abstract
The method of anticoagulation in patients undergoing major vascular surgery with a history of heparin-induced thrombocytopenia (HIT) is controversial. We present two cases in which a bolus only technique using recombinant hirudin (Lepirudin or Refludan) was used successfully in patients with HIT scheduled for vascular surgery.
Medical subject headings
- Anticoagulants
- Heparin
- Hirudins
- Recombinant Proteins
- Thrombocytopenia