Clinically relevant rat model for testing BOLD functional MR imaging techniques by using single-shot echo-planar imaging at 1.5 T.
basic_science · Level V
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Abstract
By using a 1.5-T whole-body magnetic resonance (MR) imager, a high-spatial-resolution single-shot echo-planar technique was developed to perform blood oxygen level dependent functional MR imaging of rat sensory cortex during forepaw stimulation. This technique produced cubic 1-mm(3) voxels. Signal-to-noise ratio was 140-160 (43-44 dB). Optimal effective echo time was 50 msec. This system should prove useful for developing new functional MR imaging techniques with rapid adaptation to human use.
Medical subject headings
- Brain
- Echo-Planar Imaging
- Magnetic Resonance Imaging
- Oxygen