Immunogenicity of pneumococcal vaccine in heart transplant recipients.

Blumberg, E A; Brozena, S C; Stutman, P; Wood, D; Phan, H M; Musher, D M · Clin Infect Dis · 2001

case_series · Level IV

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Abstract

To assess the immunogenicity of pneumococcal vaccine in recipients of heart transplants, we immunized 35 long-term transplantation survivors with pneumococcal vaccine and measured the pre- and postvaccination IgG antibody titers to 5 representative vaccine capsular polysaccharides. Responses of heart transplant recipients to pneumococcal vaccine antigens were generally suppressed.

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