Azithromycin and gentamicin therapy for the treatment of humans with brucellosis.
case_series · Level IV
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- Record sourced from PubMed, PMID 11170962.
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Abstract
Ten patients with brucellosis were treated with azithromycin and gentamicin to assess the treatment's safety and efficacy. Seven patients had an excellent therapeutic response at the end of therapy; however, relapse was noted in 3. When relapse was considered in combination with an initial lack of efficacy, 5 patients (50%; 95% confidence interval, 18.7%-81.3%) did not respond to therapy; these results do not favor the use of azithromycin to treat brucellosis in humans.
Medical subject headings
- Anti-Bacterial Agents
- Azithromycin
- Brucellosis
- Gentamicins