Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine.
case_report · Level V
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- Record sourced from PubMed, PMID 11174414.
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Abstract
Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection. Severe rash, including the Stevens-Johnson syndrome (SJS), is the major toxicity of nevirapine and is described in the package labeling with a prominent, boxed warning. Though physicians treating large populations of patients with HIV are well aware of this complication, only one other report of nevirapine-associated SJS has been documented in the dermatology literature. We describe 2 cases of SJS related to nevirapine use and review the literature on this newly recognized association.
Medical subject headings
- Anti-HIV Agents
- HIV Infections
- HIV-1
- Nevirapine
- Stevens-Johnson Syndrome