Surfactant protein-A gene locus associated with recurrent otitis media.

Rämet, M; Löfgren, J; Alho, O P; Hallman, M · J Pediatr · 2001

case_control · Level III

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Abstract

Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

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