Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin: case report.
case_report · Level V
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Abstract
We report the case of a 25-year-old HIV-negative man with disseminated multidrug-resistant tuberculosis (MDRTB), who-on a retreatment regimen-experienced total resolution of TB miliary disease, but progressive TB meningitis. Therefore, intrathecal treatment with amikacin and levofloxacin was instituted, with successful clinical and microbiological results.
Medical subject headings
- Amikacin
- Anti-Bacterial Agents
- Anti-Infective Agents
- Levofloxacin
- Ofloxacin
- Tuberculosis, Meningeal
- Tuberculosis, Multidrug-Resistant