Idiopathic thrombocytopenic purpura and MMR vaccine.

Miller, E; Waight, P; Farrington, C P; Andrews, N; Stowe, J; Taylor, B · Arch Dis Child · 2001

case_control · Level III

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Abstract

A CAUSAL ASSOCIATION BETWEEN MEASLES: mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.

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